Neoplasia — Flashcards

Flashcard 291: Categories of proto-oncogenes include: 1) _____ 2) Growth factor receptors 3) Signal transducers 4) Nuclear regulators 5) Cell cycle regulators

Answer: Growth factors

Flashcard 292: Paragangliomas are tumors of _____

Answer: glomus cells

Extra: - These are analogous to chromaffin cells, except for the parasympathetic nervous system - these are not tumors of glomus bodies (aka glomus tumor found under the finger nails)

Flashcard 293: How does hepatocellular carcinoma spread? _____

Answer: Hematogenously

Extra: * Liver juice on lungs and right side of heart = HCC metastasizes to lungs & heart hematogenously Atlas:

Flashcard 294: Lynch syndrome progresses to _____ cancer in ~ 80% of patients

Answer: colorectal

Extra: Atlas:

Flashcard 295: Osteosarcoma is a malignant proliferation of _____

Answer: osteoblasts

Extra: Atlas:

Flashcard 296: Warthin tumor is a cystic salivary gland tumor with abundant lymphocytes and _____

Answer: germinal centers

Extra: Atlas:

Flashcard 297: HPV has a predilection for what type of epithelium? _____

Answer: Stratified squamous epithelium

Flashcard 298: _____ is a protein from high-risk HPV that binds to p53

Answer: E6

Flashcard 299: One hallmark of cancer is the ability to be _____ signal self-sufficient

Answer: growth

Flashcard 300: Adult T-cell leukemia/lymphoma is caused by the _____ virus

Answer: HTLV-1

Extra: Other: