Neoplasia — Flashcards

Flashcard 191: Which tumor suppressor gene is associated with breast, prostate and endometrial cancer? _____

Answer: PTEN

Flashcard 192: What demographic is associated with osteochondroma? _____

Answer: Males < 25 years old

Extra: Atlas:

Flashcard 193: Surface alveolar growth is also called _____

Answer: lepidic growth pattern

Flashcard 194: Which ovarian neoplasm is most commonly associated with an increased AFP? _____

Answer: Yolk sac (endodermal sinus) tumor

Flashcard 195: _____ is a malignant tumor of skeletal muscle

Answer: Rhabdomyosarcoma

Extra: Atlas:

Flashcard 196: _____ is a lymphoid malignancy that forms a discrete mass, whereas _____ is a lymphoid or myeloid malignancy with widespread involvement of the blood and bone marrow.

Answer: Lymphoma

Extra: Lymphoma typically refers to a discrete tumor mass (e.g., in a lymph node), whereas leukemia refers to widespread involvement of the blood and bone marrow.

Flashcard 197: In Lymphoma, which is monoclonal, the kappa to lambda light chain ratio _____ or is inverted

Answer: increases to > 6:1

Extra: "Can get as high as 20:1"

Flashcard 198: In **Lymphoplasmacytic Lymphoma**, bone marrow biopsy displays _____% **lymphoplasmacytic** cells in relation to bone marrow cells.

Answer: > 10

Flashcard 199: Viruses such as EBV, HHV-8, HBV/HCV, etc are said to be _____ viruses due to them causing cancer

Answer: oncogenic

Flashcard 200: Follicular lymphoma is distinguished from reactive follicular hyperplasia by lack of _____ in germinal centers

Answer: tingible body macrophages

Extra: Other: