Neoplasia — Flashcards

Hand-Schuller-Christian disease is a _____ proliferation (benign or malignant) of Langerhans cells

Mutations in which tumor suppressor genes can lead to Wilms Tumors?_____

Which tumor suppressor gene is associated with pancreatic cancer?_____

_____ is a malignant cartilage-forming tumor

_____ is a cystic tumor composed of fetal tissue derived from two or three embryologic layers (e.g. hair, teeth, bone, skin, gut, thyroid, etc)

Embryonal carcinoma is a testicular germ cell tumor that often has a _____ morphology

The adenoma-carcinoma sequence begins with _____ gene mutations

Embryonal carcinoma is a non-seminoma germ cell tumor and therefore has a relatively _____ prognosis

If a patient inherits or develops a mutation in a _____ gene, the complementary allele must be deleted/mutated before cancer develops

What is the main distinguishing feature between follicular adenoma and follicular carcinoma of the thyroid?_____