Transcription/translation — Flashcards

Flashcard 171: The _____ of tRNA contains the TΨC sequence (ribothymidine, pseudouridine, cytidine) necessary for tRNA-ribosome binding

Answer: T-arm

Flashcard 172: _____ is a specific transcription factor that binds kB elements, which regulates expression of many genes in the immune system

Answer: Nuclear factor kappa B (NF-kB)

Flashcard 173: _____ proteins are specific transcription factors that regulate gene expression during development

Answer: Homeodomain

Flashcard 174: In the final step of translation elongation, _____ of the ribosome occurs, advancing the ribosome 3 nucleotides towards the 3' end of mRNA

Answer: translocation

Flashcard 175: In the ER, co-translational _____ adds sugars onto the amino acid asparagine

Answer: N-glycosylation

Flashcard 176: Once bound (activated), the glucocorticoid receptor enters the nucleus and binds to _____ to regulate gene transcription

Answer: glucocorticoid response elements

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 177: The two ribosomal subunits in eukaryotes are _____S and _____S making _____S

Answer: 60

Flashcard 178: ACTH is a(n) _____ hormone

Answer: polypeptide

Flashcard 179: _____ will result in: HbA = 0% HbS = 0% HbF ≈ 97.5% HbA2 ≈ 2.5%

Answer: β-thalassemia major (β0/β0)

Flashcard 180: In an experiment studying Burkitt lymphoma, Western blot analysis shows a significant decrease in c-Myc protein levels following treatment, while c-Myc mRNA levels remain unchanged. What process was most likely directly interrupted by this treatment?

Answer: mRNA translation