Transcription/translation US Medical PG Flashcards - Medical Study Cards
Master Transcription/translation with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Transcription/translation Flashcard Deck - 10 Cards
Flashcard 151: A(n) _____ mutation occurs when there is a deletion or insertion of a number of nucleotides not divisible by 3, resulting in misreading of all nucleotides downstream
Answer: frameshift
Extra:
Watch DNA Mutations [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-dna-mutations?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-mutations-damage-and-repair?index=2]
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 152: The _____ strand is the strand of dsDNA that is NOT used during transcription, but is identical to mRNA (substitute T/U)
Answer: coding
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=2]
https://onlinemeded.org?ref=anki
Flashcard 153: In the first step of alternative splicing, the primary transcript (hnRNA) combines with _____ and other proteins to form the spliceosome
Answer: small nuclear ribonucleoproteins (snRNPS)
Extra:
Watch Transcription and RNA Processing [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-rna-transcription-and-rna-processing?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 154: Capped, tailed, and spliced hnRNA is called _____
Answer: mRNA
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=6]
https://onlinemeded.org?ref=anki
Flashcard 155: Aminoacyl-tRNA synthetase requires _____ and releases inorganic PPi
Answer: ATP
Extra:
Watch Protein Synthesis [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-protein-protein-synthesis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=8]
https://onlinemeded.org?ref=anki
Flashcard 156: Thyroglobulin synthesis (as part of thyroid hormone synthesis) occurs in the _____ and _____ of the thyroid follicular cells
Answer: RER
Extra:
https://onlinemeded.org/spa/endocrinology/thyroid/acquire?ref=anki
Flashcard 157: What would happen if there is absent or dysfunctional signal recognition particles (SRPs)?
_____
Answer: proteins accumulate in the cytosol
Extra:
https://onlinemeded.org?ref=anki
Flashcard 158: What is the smaller ribosomal subunit used in eukaryotic translation?
_____
Answer: 40s
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=10]
https://onlinemeded.org?ref=anki
Flashcard 159: For the Kozak consensus sequence (gccgccRccAUGG) to work properly, the R group positioned 3 bases upstream must be a(n) _____
Answer: purine
Extra:
https://onlinemeded.org?ref=anki
Flashcard 160: On the N terminal side of newly synthesized protein, a stretch of 10-15 hydrophobic amino acids forms the _____ sequence
Answer: N-terminal signal
Extra:
https://onlinemeded.org?ref=anki
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