Transcription/translation — Flashcards

Flashcard 141: The N-terminal signal sequence of a newly synthesized protein is bound by a(n) _____, which attaches the complex to the ER membrane

Answer: signal recognition particle (SRP)

Flashcard 142: At the 3' end of a tRNA molecule is a(n) _____ sequence, which is the amino acid acceptor stem

Answer: 5'-CCA-3'

Flashcard 143: In the Golgi apparatus, post-translational _____ adds sugars onto the amino acids serine and threonine

Answer: O-glycosylation

Flashcard 144: Accurate base pairing is usually required only in the first two nucleotide positions of a mRNA codon because codons differing in the 3rd "_____" position may code for the same amino acid

Answer: wobble

Flashcard 145: One co-transcriptional modification is the addition of a(n) _____ at the 5' end

Answer: 7-methylguanosine cap

Extra: Watch associated Bootcamp video

Flashcard 146: After T3 binds its nuclear receptor, the T3-receptor complex binds to a thyroid-regulatory element on DNA, where it stimulates _____

Answer: DNA transcription

Flashcard 147: What process takes RNA and makes DNA? _____

Answer: reverse transcription

Flashcard 148: The enzyme which adds TTAGGG to 3' ends of chromosomes to avoid loss of genetic material with every duplication is known as _____

Answer: Telomerase

Flashcard 149: A(n) _____ mutation occurs when there is a deletion or insertion of a number of nucleotides not divisible by 3, resulting in misreading of all nucleotides downstream

Answer: frameshift

Flashcard 150: Mutant huntingtin protein in Huntington's Disease leads to transcriptional repression by inhibiting _____

Answer: histone acetyltransferase