Transcription/translation — Flashcards

Flashcard 111: How many different RNA polymerases do prokaryotes have? _____

Answer: One (makes all 3 kinds of RNA)

Flashcard 112: _____ are sites where negative regulators (repressors) bind to DNA

Answer: Silencers

Flashcard 113: DNA/RNA polymerase always read in the _____ direction

Answer: 3' to 5'

Flashcard 114: Prokaryotic transcription terminates when there is a "_____" sequence, which is a(n) GC rich region

Answer: stem-loop

Flashcard 115: Enhancers serve as binding sites for _____ transcription factors

Answer: specific

Flashcard 116: Von Hippel-Lindau disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of _____

Answer: HIF1a

Extra: * "VHL = 3 letters" ; HIF1a allows production of excess EPO

Flashcard 117: Which sequence of bases is a start codon (methionine) in mRNA? _____

Answer: AUG

Flashcard 118: Targets of JAK (tyrosine kinase associated-receptor pathway) include _____, which cause transcription of new mRNAs and new protein synthesis

Answer: STATs

Flashcard 119: What is the total size of the ribosome used in prokaryotic translation? _____

Answer: 70s

Flashcard 120: What is the larger ribosomal subunit used in eukaryotic translation? _____

Answer: 60s