Anticancer Drugs — Flashcards

Bleomycin has a _____ binding region and an iron binding region

Imatinib can inhibit the receptor tyrosine kinase _____, making it useful for GI Stromal Tumors (GIST)

_____ is a GnRH antagonist used to treat prostate cancer.

Proteasomal inhibitors (_____) are antineoplastics that inhibit cell cycle progression at the G2-M phase

Hint: suffix

Thymidine synthesis inhibitor (MTX, 5-FU, hydroxyurea) use can result in _____-suppression and pan-cytopenia

Ruxolitinib is used to treat chronic myeloproliferative disorders that have _____ mutations including myelofibrosis and polycythemia vera

-Posides (Topoisomerase II inhibitor antineoplastics) are used to treat solid tumors, particularly _____ cancer and small cell lung cancer

_____ and dabrafenib work as BRAF kinase inhibitors

Topotecan, a Topoisomerase I inhibitor, is used to treat cancers of the _____ system and small cell lung cancer

Alemtuzumab is primarily used to treat _____ and Multiple Sclerosis