Plant Alkaloids — Flashcards

Which anticancer agent is associated with secondary leukemia?_____

Which of the cytotoxic microtubule inhibitors bind β-tubulin and inhibit polymerization? _____

Which two drugs are cytotoxic vinca alkaloids? _____

Etoposide and teniposide have activity against both _____ and solid tumor malignancies

Taxanes are used to treat for _____ and ovarian carcinomas

As two classes of antineoplastic agents that modulate microtubule structure, the distinction lies in that vinca-alkaloids prevent microtubule _____ whereas taxanes prevent microtubule disassembly

Which of the cytotoxic microtubule inhibitors prevent mitotic spindle formation?_____

Antineoplastic agents extracted from the Periwinkle plant is: _____ also called Catharanthus roseus

_____ is a drug of choice for mesothelioma.

Hint: Antifolate drug

Cetuximab is a monoclonal antibody against the _____ Receptor most commonly used to treat Stage IV colorectal cancer