Targeted Therapy — Flashcards

Imatinib can inhibit the receptor tyrosine kinase _____, making it useful for GI Stromal Tumors (GIST)

Drug of choice for EGFR T790M mutation of Non-Small Cell Lung Cancer is

Which kinase inhibitor has recently been approved for rx of breast cancer (Her2 +ve) with brain mets?_____

Nivolumab is used as a checkpoint inhibitor in _____ lymphoma, advanced melanoma, advanced NSCLC that is previously treated, _____ carcinoma, and advanced head and neck cancers.

Osimertinib, as a third-generation EGFR inhibitor is effective against NSCLC with _____ mutation

Vemurafenib treats _____ positive malignant melanoma

_____ and olaparib are PARP inhibitors approved for the treatment of advanced ovarian cancer.

Common chimeric antitumor monoclonal antibodies include _____ and cetuximab

Antineoplastic agents extracted from the Periwinkle plant is: _____ also called Catharanthus roseus

Cetuximab is a monoclonal antibody against the _____ Receptor most commonly used to treat Stage IV colorectal cancer