Anticancer Drugs — Flashcards

Present chemotherapy regimen used for breast cancer is ACT, i.e., _____, Cyclophosphamide, and Taxane (Paclitaxel)

Cyclophosphamide can result in _____, with resultant hypo-natremia

What anti-neoplastic agents may cause interstitial restrictive lung disease? _____, busulfan, methotrexate, and procarbazine

Cyclophosphamide use can result in _____, with the bladder toxicity arising from the metabolite acrolein

Paclitaxel and other taxanes can be used to treat _____ and breast carcinoma

Etoposide and teniposide have activity against both _____ and solid tumor malignancies

Anthracyclines (doxorubicin, daunorubicin) treat both _____ malignancies and solid tumors

Bleomycin has a _____ binding region and an iron binding region

Thymidine synthesis inhibitor (MTX, 5-FU, hydroxyurea) use can result in _____-suppression and pan-cytopenia

Imatinib can inhibit the receptor tyrosine kinase _____, making it useful for GI Stromal Tumors (GIST)