Anticancer Drugs — Flashcards

Ruxolitinib is used to treat chronic myeloproliferative disorders that have _____ mutations including myelofibrosis and polycythemia vera

Because Cytarabine targets lymphocytes, it is indicated for _____ as well as Non-Hodgkins Lymphoma

Imatinib can inhibit the receptor tyrosine kinase _____, making it useful for GI Stromal Tumors (GIST)

Procarbazine has notable side effects; including _____ toxicity and leukemia*bonus: pts shouldn't eat what food?

Topotecan, a Topoisomerase I inhibitor, is used to treat cancers of the _____ system and small cell lung cancer

-Posides (Topoisomerase II inhibitor antineoplastics) are used to treat solid tumors, particularly _____ cancer and small cell lung cancer

Alemtuzumab is primarily used to treat _____ and Multiple Sclerosis

Proteasomal inhibitors (_____) are antineoplastics that inhibit cell cycle progression at the G2-M phase

Hint: suffix

Anthracyclines (doxorubicin, daunorubicin) treat both _____ malignancies and solid tumors

Thymidine synthesis inhibitor (MTX, 5-FU, hydroxyurea) use can result in _____-suppression and pan-cytopenia