Anticancer Drugs — Flashcards

Anthracyclines (doxorubicin, daunorubicin) _____ into DNA, blocking DNA and RNA synthesis

Humoral hypercalcemia of malignancy may be treated with _____ or pamidronate, which inhibits bone resorption

Bleomycin is an antineoplastic antibiotic indicated for _____ as well as cancers of the reproductive system

Bleomycin treats both _____ malignancies and solid tumors

Which chemotherapeutic drugs cross-link DNA at the guanine N-7?_____

Platinum analogs are associated with _____-toxicity and oto-toxicity

When injected intravenously, 5FU can be used to treat _____ cancer and pancreatic cancer

Ifosfamide attaches an alkyl group to the _____ of guanine

Azathioprine is converted to _____, a cytotoxic purine analog

Which of the cytotoxic microtubule inhibitors prevent mitotic spindle formation?_____