Autoimmune Skin Diseases — Flashcards

Flashcard 21: Bullous form of pyoderma gangrenosum is associated with _____ malignancy

Answer: hematological

Flashcard 22: Discoid rashes resembling Discoid lupus erythematosus may also be seen in _____ lupus erythematosus

Answer: Systemic

Flashcard 23: Mucous membrane lesions are quite _____ in Lichen nitidus.

Answer: rare

Flashcard 24: _____ is a type of linear morphea presenting as scarring alopecia

Answer: En coup de Sabre

Flashcard 25: Which clinical form of Discoid Lupus Erythematosus (DLE) is the most common?

Answer: Localized (circumscribed) form

Extra: Localized Discoid Lupus Erythematosus (DLE) involves the skin only above the neck (e.g., face, scalp, ears). It is more common than generalized DLE, which involves areas both above and below the neck.

Flashcard 26: Dermatomyositis may present with _____, which are macules or patches involving the skin over the interphalangeal joints, elbows, and knees

Answer: Gottron's sign

Flashcard 27: The characteristic periorbital distribution of the rash in neonatal lupus erythematosus is known as _____ eyes (also called 'owl eye' or 'eye mask' appearance).

Answer: Raccoon

Extra: Neonatal Lupus Erythematosus (NLE) is caused by the transplacental passage of maternal anti-Ro (SSA) and/or anti-La (SSB) antibodies. The most common manifestations are: 1. **Cutaneous:** Erythematous annular or polycyclic plaques, characteristically in a periorbital distribution (**'raccoon eyes'**, 'owl eye', or 'eye mask' appearance). These usually resolve without scarring as maternal antibodies wane. 2. **Cardiac:** Congenital heart block (permanent and may require a pacemaker).

Flashcard 28: The most common cutaneous manifestation of Systemic Lupus Erythematosus is _____

Answer: photosensitivity

Flashcard 29: Extent of skin sclerosis in Systemic Sclerosis can be measured, using _____ score

Answer: modified Rodnan skin (MRSS)

Flashcard 30: Ragged cuticle and periungual erythema are nail changes is seen in _____

Answer: dermatomyositis