Relapsing Polychondritis — Flashcards

Flashcard 1: Pathergy test is _____ in pyoderma gangrenosum

Answer: positive

Flashcard 2: _____ may present with Gottron papules, which are red papules on the PIP joints, DIP joints and MCP joints.

Answer: Dermatomyositis

Flashcard 3: Dermatomyositis may present with _____, which are macules or patches involving the skin over the interphalangeal joints, elbows, and knees

Answer: Gottron's sign

Flashcard 4: Autoantibodies seen in dermatomyositis include anti-_____, anti-NXP2, anti-MDA5, and anti-TIF1-gamma.

Answer: Mi-2

Flashcard 5: The most common finding in Neonatal Lupus Erythematosus is erythematous eruption around face and eyes, also called _____ sign

Answer: raccoon

Flashcard 6: First line rx for oral lichen planus is _____ ointment, soluble prednisolone/betamethasone tablets (for mouthwash) and oral prednisolone (for severe erosive disease)

Answer: clobetasol propionate

Flashcard 7: Anti-_____ antibodies are associated with dermatomyositis featuring gottron papules and heliotrope rash

Answer: Mi2

Flashcard 8: Which clinical form of Discoid Lupus Erythematosus (DLE) is the most common?

Answer: Localized (circumscribed) form

Extra: Localized Discoid Lupus Erythematosus (DLE) involves the skin only above the neck (e.g., face, scalp, ears). It is more common than generalized DLE, which involves areas both above and below the neck.

Flashcard 9: The characteristic skin changes seen in **lichenoid tissue reactions** (e.g., Lichen Planus) are _____.

Answer: violaceous, polygonal, flat-topped papules

Extra: Wickham striae (fine white reticular lines) are often visible on the surface of these papules. Histologically, lichenoid reactions are characterized by 'saw-tooth' rete ridges, basal cell vacuolar degeneration, and a band-like lymphocytic infiltrate at the dermo-epidermal junction.

Flashcard 10: _____ may present with a malar rash that is similar to SLE

Answer: Dermatomyositis