Management of Autoimmune Skin Diseases — Flashcards

Flashcard 1: _____ is an autoimmune destruction of desmosomes between keratinocytes

Answer: Pemphigus vulgaris

Flashcard 2: _____ disease is associated with dermatitis herpetiformis, which are small, herpes-like vesicles on the skin

Answer: Celiac

Flashcard 3: _____  is a term used in preference to localized scleroderma , showing sclerosis, fibrosis, and atrophy in the skin and subcutaneous tissues

Answer: Morphoea

Flashcard 4: Antibodies to the _____ antigen are seen associated with Subacute Cutaneous Lupus Erythematosus

Answer: Ro/SS A

Flashcard 5: Discoid lupus erythematosus is a benign inflammatory disorder of the skin, most frequently involving the _____ and scalp

Answer: face

Flashcard 6: _____ is an autoimmune destruction of hemidesmosomes between basal cells and the underlying basement membrane

Answer: Bullous pemphigoid

Flashcard 7: Anti-_____ antibodies are associated with dermatomyositis featuring paraneoplastic syndrome

Answer: P155/P140

Flashcard 8: Third line rx for oral lichen planus is _____ agents

Answer: immunosuppressive

Flashcard 9: Scleroderma like skin changes is a paraneoplastic syndrome associated with _____ tumor

Answer: Carcinoid

Flashcard 10: The characteristic skin changes seen in **lichenoid tissue reactions** (e.g., Lichen Planus) are _____.

Answer: violaceous, polygonal, flat-topped papules

Extra: Wickham striae (fine white reticular lines) are often visible on the surface of these papules. Histologically, lichenoid reactions are characterized by 'saw-tooth' rete ridges, basal cell vacuolar degeneration, and a band-like lymphocytic infiltrate at the dermo-epidermal junction.