Immunobullous Disorders — Flashcards

Flashcard 1: _____ Lupus Erythematosus presents most commonly as a non scarring papulosquamous eruptions in 2/3rd cases

Answer: Subacute Cutaneous

Flashcard 2: _____ is an autoimmune destruction of desmosomes between keratinocytes

Answer: Pemphigus vulgaris

Flashcard 3: Antibodies to the _____ antigen are seen associated with Subacute Cutaneous Lupus Erythematosus

Answer: Ro/SS A

Flashcard 4: Anti-_____ antibodies are associated with dermatomyositis featuring gottron papules and heliotrope rash

Answer: Mi2

Flashcard 5: Degeneration of keratinocytes in lichen planus leads to the formation of spaces in the epidermis known as _____

Answer: Max-Joseph Spaces

Flashcard 6: Drug of choice in dermatitis herpetiformis is:

Answer: Dapsone

Flashcard 7: The characteristic skin changes seen in **lichenoid tissue reactions** (e.g., Lichen Planus) are _____.

Answer: violaceous, polygonal, flat-topped papules

Extra: Wickham striae (fine white reticular lines) are often visible on the surface of these papules. Histologically, lichenoid reactions are characterized by 'saw-tooth' rete ridges, basal cell vacuolar degeneration, and a band-like lymphocytic infiltrate at the dermo-epidermal junction.

Flashcard 8: _____ may present with a malar rash that is similar to SLE

Answer: Dermatomyositis

Flashcard 9: _____ may present with a "heliotrope" rash, which is an erythematous periorbital rash

Answer: Dermatomyositis

Flashcard 10: _____ may present with Gottron papules, which are red papules on the PIP joints, DIP joints and MCP joints.

Answer: Dermatomyositis