Scleroderma and Morphea — Flashcards

Flashcard 1: What is the most common type of morphoea?_____

Answer: Plaque morphea

Flashcard 2: _____  is a term used in preference to localized scleroderma , showing sclerosis, fibrosis, and atrophy in the skin and subcutaneous tissues

Answer: Morphoea

Flashcard 3: Graves disease is associated with _____ myxedema which occurs due to activation of dermal fibroblasts

Answer: pretibial

Flashcard 4: Anti-_____ antibodies are associated with dermatomyositis featuring paraneoplastic syndrome

Answer: P155/P140

Flashcard 5: Lichen sclerosus is characterized by _____ of the epidermis and fibrosis (sclerosis) of the dermis

Answer: thinning

Flashcard 6: Dermatomyositis may present with _____, which are macules or patches involving the skin over the interphalangeal joints, elbows, and knees

Answer: Gottron's sign

Flashcard 7: Scleroderma like skin changes is a paraneoplastic syndrome associated with _____ tumor

Answer: Carcinoid

Flashcard 8: The characteristic skin changes seen in **lichenoid tissue reactions** (e.g., Lichen Planus) are _____.

Answer: violaceous, polygonal, flat-topped papules

Extra: Wickham striae (fine white reticular lines) are often visible on the surface of these papules. Histologically, lichenoid reactions are characterized by 'saw-tooth' rete ridges, basal cell vacuolar degeneration, and a band-like lymphocytic infiltrate at the dermo-epidermal junction.

Flashcard 9: _____ may present with a malar rash that is similar to SLE

Answer: Dermatomyositis

Flashcard 10: _____ may present with a "heliotrope" rash, which is an erythematous periorbital rash

Answer: Dermatomyositis