Nucleic Acid Biochemistry — Flashcards

Primary miRNA is converted to _____ intranuclearly by the enzyme complex DROSHA

DNA & RNA are made of _____ connected via a phosphodiester bond

Diphtheria toxin causes _____ of EF-2 (elongation factor-2), thus inhibiting protein synthesis

Cells generate purines for cell growth through either _____ production or through the salvage pathway

_____ radiation results in the formation of double-stranded breaks in DNA and hydroxyl free radicals which damage DNA

During DNA strand elongation, the _____ of the incoming dNTP is the target of 3' hydroxyl attack.

All 4 types of DNA are _____ handed except Z-DNA

The _____ operon is a repressible operon that is turned off whenever tryptophan is added to the growth medium.

The enzyme _____ is an important enzyme for de novo purine production, which converts PRPP to an intermediate used in the generation of IMP

Adenosine is converted to _____ via the enzyme adenosine deaminase (purine salvage)