Nucleic Acid Biochemistry — Flashcards

In the RISC complex, miRNAs can modulate mRNA function by stimulating _____ degradation or inhibiting translation by targeting eIF4 translation factor, in case of imperfect complementarity.

In the first step of pyrimidine synthesis, glutamine and CO2 are combined to form _____ via the enzyme carbamoyl phosphate synthetase II (requires 2 ATP)

When the _____ domain is removed from DNA polymerase I, the remaining fragment is called as Klenow fragment.

Conversion of dUMP to dTMP via Thymidylate synthase converts the cofactor _____ to DHF

Every intron has a 5' _____ site and a 3' acceptor site, which are brought together to form the Lariat-shaped loop

Xanthine may be converted to _____ via the enzyme xanthine oxidase

Ribose-5-phosphate is converted to _____ via the enzyme PRPP synthetase

_____ DNA is generated by the hydrogen bonding of a third strand into a major groove of B-DNA.

At the _____' end of a tRNA molecule is a 5'-CCA-3' sequence, which is the amino acid acceptor stem

RNA polymerase _____ makes tRNA and 5S rRNA