Purine Metabolism and Disorders — Flashcards

The enzyme _____ is an important enzyme for de novo purine production, which converts PRPP to an intermediate used in the generation of IMP

Glutamine-PRPP amidotransferase (purine synthesis) is regulated by negative feedback via _____, IMP, and GMP

The disadvantage of using CPDA-1 is that it increases _____ stone formation.

Besides its role in **thymidine** production, **THF** is also involved in the formation of _____, as well as some amino acids

Xanthine may be converted to _____ via the enzyme xanthine oxidase

Xanthine is converted to _____ by xanthine oxidase

Hypoxanthine is converted to _____ via xanthine oxidase

microRNA often leads to the _____ of target mRNA, thus causing decreased translation into protein

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)