Nucleic Acid Biochemistry — Flashcards

Hypoxanthine is converted to _____ via xanthine oxidase

Inosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

RNA polymerase _____ makes mRNA

microRNA often leads to the _____ of target mRNA, thus causing decreased translation into protein

One co-transcriptional modification is the addition of a _____ at the 5' end

Xanthine is converted to _____ by xanthine oxidase

The enzymes that repair mismatched base mutations (eg. spontaneous/toxic deaminations) are _____ and DNA ligase

In the first step of alternative splicing, the primary transcript (hnRNA) combines with _____ and other proteins to form the spliceosome

Every intron has a 5' _____ site and a 3' acceptor site, which are brought together to form the Lariat-shaped loop

Conversion of dUMP to dTMP via Thymidylate synthase converts the cofactor _____ to DHF