Anti-neoplastic drugs — Flashcards

Flashcard 1: anastrazole

Answer:

Extra: breast cancer in postmenopausal womenaromatase inhibitor

Flashcard 2: exemestane

Answer:

Extra: breast cancer in postmenopausal womenaromatase inhibitor

Flashcard 3: alkylating agents

Answer: absence of digits (and multiple varied anomalies)

Flashcard 4: folate antagonists

Answer: neural tube defects

Flashcard 5: methotrexate (MTX)

Answer:

Extra: inhibits eukaryotic dihydrofolate reductase

Flashcard 6: 5-flourouracil (5-FU)

Answer:

Extra: inhinits thymidylate synthase

Flashcard 7: 6-mercaptopurine (6-MP)

Answer:

Extra: blocks de novo purine synthesis

Flashcard 8: hydroxyurea

Answer:

Extra: inhibits ribonucleotide reductase