Systemic Pathology — Flashcards

Toxic multinodular goiter is most often due to _____ mutations (60% of cases)

Renal papillary necrosis may be caused by severe acute _____

Which joint pathology is caused by a synovitis leading to formation of a pannus (inflamed granulation tissue)?_____

What HLA subtype is associated with multiple sclerosis? _____

Sickle cell trait/disease is protective against which species of **Plasmodium**?

Loss of membrane blebs in hereditary spherocytosis renders RBCs _____ instead of disc-shaped

Is the metabisulfite screen positive in sickle cell disease or trait? _____

What renal pathology is associated with eosinophils in the urine? _____

What is the mode of inheritance of Chediak-Higashi syndrome? _____

Type II MPGN is associated with _____ circulating levels of C3