Systemic Pathology — Flashcards

What chromosomal abnormality is associated with Edwards syndrome?_____

Which immunodeficiency is caused by failure to repair DNA double strand breaks? _____

Is Klinefelter syndrome characterized by the presence of an inactivated X chromosome (Barr body)?_____

Sickle cell anemia is characterized by expansion of hematopoiesis into facial bones, leading to "_____ facies"

Which classes of immunoglobulin are normal or decreased in Wiskott-Aldrich syndrome? _____

SCID may be caused by MHC class _____ deficiency

Which immunodeficiency presents with defective class switching? _____

Which classes of immunoglobulin are decreased in Bruton agammaglobulinemia? _____

Hemophagocytic lymphohistiocytosis is characterized by very increased levels of _____.

What pathology is associated with disruption of the cranial end of the neural tube? _____