Systemic Pathology US Medical PG Flashcards - Medical Study Cards
Master Systemic Pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Systemic Pathology Flashcard Deck - 10 Cards
Flashcard 571: In alpha thalassemia, there is a(n) _____ in RBC count
Answer: increase
Extra:
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Flashcard 572: Podocyte fusion or "effacement" on electron microscopy
_____
Answer: Minimal change disease
left: normal; right: MCD
Extra:
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Flashcard 573: What conditions are associated with target cells on blood smear?
_____
Answer: HbC disease
Asplenia
Liver disease
Thalassemia
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Flashcard 574: Multiple sclerosis = _____
Answer: MRI
Extra:
https://onlinemeded.org/spa/neurology/weakness/acquire?ref=anki
Flashcard 575: Cellular cresents in Bowman capsule
_____
Answer: Rapidly progressive crescentic glomerulonephritis
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Flashcard 576: How do complement levels change in an acute lupus flare?
_____
Answer: Decrease
Extra:
https://onlinemeded.org/spa/rheumatology/approach-to-joint-pain/acquire?ref=anki
Flashcard 577: _____ is the most common cause of spontaneous intraparenchymal hemorrhage
Answer: Amyloid angiopathy
Extra:
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Flashcard 578: What are the followings in relation to splenomegaly?
-Inflammatory infiltration
-Myeloproliferative disorder
-Passive splenic congestion
-Presence of circulating immune complexes
-Red pulp hyperplasia
-Undegraded metabolite accumulation
Answer: Inflammatory infiltration: could lead to splenomegaly by chronic infections.
-Myeloproliferative disorder: splenomegaly by Leukemia & lymphoma.
-Passive splenic congestion: Splenomegaly by portal hypertension, splenic vein thrombosis, or congestive heart failure.
-Presence of circulating immune complexes: splenomegaly by infective endocarditis.
-Red pulp hyperplasia. splenomegaly by removing deform RBC in spleen due to lack of ATP.
-Undegraded metabolite accumulation: splenomegaly caused by lysosomal storage diseases ( Nieman pick & gaucher disease) due to accumulation of sphyngomyelin & glucocerebrosides.
Flashcard 579: What kind of pathology those organs will most likely develop secondary to mutation?
-Aorta
-Heart
-Joints
-Liver
-Pancreas
Answer: Aorta: Marfan syndrome due to defect in fibrillin-1.
-Heart & liver: glycogen storage disease
(Very Poor Carbs Metabolism)
Von Gierke - glucose-6-phosphatase deficiency (hepatomegaly)
Pompee - a1,4-glucosidase deficiency (heart, liver, & muscle)
Cori disease - a1,6-glucosidase deficiency
McArdle disease - glycogen phosphorylase.
-Pancreas: is affected in Cystic fibrosis (pancreatitis)
Flashcard 580: Sickle cell anemia is characterized by expansion of hematopoiesis into facial bones, leading to "_____ facies"
Answer: chipmunk
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