Systemic Pathology — Flashcards

Noncaseating granulomas in the lung and hilar nodes may indicate: _____

Hint: Two conditions

What pathology is associated with microcephaly, intellectual disability, and a high-pitched cry? _____, cause by deletion of short arm of chromosome _____

"Spikes" on basement membrane, "dome-like" subepithelial deposits _____

Hint: diagnosis

Vitamin K deficiency → ↑ _____ time Severe Vitamin K deficiency = ↑ _____ and _____ time

Hint: PT/PTT

What inherited hematologic pathology is associated with avascular necrosis (osteonecrosis)? _____

Osteomyelitis in adults = _____ spread Osteomyelitis in kids = _____ spread

Hint: hematogenous/contiguous

What three conditions precipitate sickling in sickle cell anemia? _____

Immunodeficiency = _____ risk of hodgkin lymphoma

Hemophilia = mixing normal plasma with patient's plasma (mixing study) = _____ PTT time Coagulation factor inhibitor = mixing normal plasma with patient's plasma (mixing study) = _____ PTT time

Hint: ↑/↓/↔

The presence of **RBC casts** or **dysmorphic RBCs** in the urine indicates that the hematuria is of _____ origin.

Hint: glomerular/non-glomerular