Systemic Pathology — Flashcards

Flashcard 331: What class of diseases is characterized by anticipation? _____

Answer: Trinucleotide repeat diseases (e.g. Huntington disease)

Flashcard 332: When HLA typing, the purpose of testing for a Mixed lymphocyte reaction is to test for MHC class _____

Answer: II (ex HLA-DR)

Flashcard 333: Progressive multifocal leukoencephalopathy results in death of _____ in the CNS

Answer: oligodendrocytes

Flashcard 334: Thyroid adenoma, cancer, and cysts all may cause which type of goiter? _____

Answer: Nodular

Extra: Atlas:

Flashcard 335: Vitamin B12 (cobalamin) deficiency is characterized by _____ polymorphonuclear cells (PMNs)

Answer: hypersegmented

Flashcard 336: A "_____" glomerular disorder is characterized by hypercellular glomeruli

Answer: proliferative

Flashcard 337: Which two pathologies may present as nephritic and/or nephrotic syndrome? _____

Answer: DPGN, MPGN

Flashcard 338: Sickle cell _____ arises when two abnormal β genes are present; results in >90% HbS in RBCs

Answer: disease

Extra: Other:

Flashcard 339: Sloughed epithelial cell accumulation in tubular lumen (obstruction) exacerbates the reduced GFR in _____

Answer: acute tubular necrosis

Flashcard 340: Berger disease is characterized by Ig_____-based immune complex deposits in the mesangium (seen with immunofluorescence)

Answer: A

Extra: Atlas: