Neoplasia — Flashcards

Which tumor suppressor gene is associated with neurofibromatosis type 2?_____

'Triple-Negative' breast cancer is negative for ER, PR, and HER2/neu and has a _____ prognosis

Interferons stimulate antitumor activity by activating _____ Cells

Homologous Recombination is defective in breast/ovarian cancers with _____ mutations

What inherited cancers (2) are associated with osteosarcoma? _____

Is chronic myeloid leukemia associated with JAK2 mutations?_____

What demographic (age group) is associated with giant cell tumor of bone? _____

Is polycythemia vera associated with JAK2 mutations?_____

The peak incidence for secondary osteosarcoma is in _____

Abnormal expression of miRNAs contributes to certain _____ (e.g. by silencing an mRNA from a tumor suppressor gene)