Neoplasia — Flashcards

The adenoma-carcinoma sequence begins with _____ gene mutations

Adenocarcinoma of the lung is _____ located

Do both alleles of a protooncogene need to be mutated in order for expression of disease?_____

Renal cell carcinoma often originates from the _____ cells of the nephron

Renal cell carcinoma is referred to as a "_____" cancer because it commonly presents as a metastatic neoplasm

Paragangliomas (also called Glomus jugulare) are tumors of _____ found in the mastoid

What is the mechanism that results in malignancy from the CDK4 oncogene?_____

What is the most common bone malignancy? _____

The overlying cartilage in osteochondroma rarely transforms to _____

Tumor cells commonly produce _____ factors (ex. FGF / VEGF), which are necessary for tumor survival and growth