Anticancer Drugs — Flashcards

Cyclophosphamide use can result in _____, with the bladder toxicity arising from the metabolite acrolein

Cyclophosphamide can result in _____, with resultant hypo-natremia

Paclitaxel and other taxanes can be used to treat _____ and breast carcinoma

Present chemotherapy regimen used for breast cancer is ACT, i.e., _____, Cyclophosphamide, and Taxane (Paclitaxel)

_____ is a cytotoxic plant alkaloid associated with peripheral neuropathy (neurotoxicity)

What anti-neoplastic agents may cause interstitial restrictive lung disease? _____, busulfan, methotrexate, and procarbazine

Thymidine synthesis inhibitor (MTX, 5-FU, hydroxyurea) use can result in _____-suppression and pan-cytopenia

_____ and dabrafenib work as BRAF kinase inhibitors

Imatinib can inhibit the receptor tyrosine kinase _____, making it useful for GI Stromal Tumors (GIST)

Bleomycin has a _____ binding region and an iron binding region