Anticancer Drugs — Flashcards

Platinum analogs are associated with _____-toxicity and oto-toxicity

Which chemotherapeutic drugs cross-link DNA at the guanine N-7?_____

Because Bevacizumab impairs sustained _____, this makes it especially useful for metastatic tumors

Antineoplastic agents extracted from the _____ plant is: Vinca alkaloidsalso called Catharanthus roseus

_____ is an immunostimulant that works by targeting the PD-1 receptor

Taxanes are used to treat for _____ and ovarian carcinomas

Actinomycin D _____ into DNA, blocking DNA and RNA synthesis

_____ and allopurinol are used prior to initiation of chemotherapy to decrease risk of urate-induced acute tubular necrosis

_____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)

Present chemotherapy regimen used for breast cancer is ACT, i.e., _____, Cyclophosphamide, and Taxane (Paclitaxel)