Anticancer Drugs — Flashcards

Which two drugs are cytotoxic vinca alkaloids?_____

Azathioprine is converted to _____, a cytotoxic purine analog

Bleomycin is an antineoplastic antibiotic indicated for _____ as well as cancers of the reproductive system

Ifosfamide can cause neurotoxicity due to buildup of its metabolite _____, which can be treated with methylene blue

Which of the cytotoxic microtubule inhibitors prevent mitotic spindle formation?_____

Humoral hypercalcemia of malignancy may be treated with _____ or pamidronate, which inhibits bone resorption

Ifosfamide attaches an alkyl group to the _____ of guanine

Anthracyclines (doxorubicin, daunorubicin) _____ into DNA, blocking DNA and RNA synthesis

When injected intravenously, 5FU can be used to treat _____ cancer and pancreatic cancer

Bleomycin treats both _____ malignancies and solid tumors