Neoplasia — Flashcards

Tumor cells can evade apoptosis / immune surveillance by downregulating expression of _____ or alternative splicing of the Fas receptor

Transitional cell carcinoma may arise via two distinct pathways: _____ and papillary

IgA antibodies against _____ and VCA should be done for screening of patients for nasopharyngeal cancer.

The Carcinoembryonic antigen (CEA) is a serum tumor marker that has minor associations with _____, breast, and medullary thyroid carcinomas

Gastric carcinoma may spread and involve the _____, also known as a Krukenberg tumor

Paragangliomas most commonly occur at the _____, known as a carotid paraganglioma

Hint: location

Order of distant metastasis in Papillary thyroid carcinoma: _____ > Bone > Liver > Brain

To remember the most common neoplasias that spread _____Embryonal carcinomaHepatocellular carcinomaSarcomaChoriocarcinomaRenal cell carcinomaFollicular carcinoma of the thyroid

Retinoblastoma is due to mutation in Rb gene located on chromosome _____q14

_____ is a tumor suppressor gene that encodes p16 which blocks the G1 to S phase of the cell cycle