Neoplasia — Flashcards

_____ carcinoma is a urinary tract cancer associated with aniline (azo) dyes

_____ is the microscopic assessment of differentiation in a cancer

The cells of _____ tumors exhibit amine precursor uptake and decarboxylation (APUD) properties.

_____ carcinoma of the lung is characterized by positive staining for chromogranin A, neuron-specific enolase, synaptophysin, and NCAM (CD56)

Loss of copies of a tumor suppressor gene (knudson two-hit hypothesis) arise from _____ (inherited) or somatic (sporadic) mutations

Tumor staging is based on _____ (c) or pathological (p) findings

_____ syndrome is a combination of: 1. Wilms tumor 2. Early-onset nephrotic syndrome 3. Male pseudohermaphroditism (gonadal dysgenesis)

_____ is the malignant proliferation of cells in the lobules of the breast with no invasion of the basement membrane

Metastasis oncogenes such as _____ and TWIST encode transcription factors whose primary function is to promote epithelial-to-mesenchymal transition (EMT).

_____ is a malignant germ cell tumor composed of mononuclear cytotrophoblasts and multinuclear syncytiotrophoblasts, but with absent villi