Neoplasia — Flashcards

_____ lung carcinoma arises from neuroendocrine (Kulchitsky) cells, which are small, dark blue cells

_____ lung carcinoma may produce the anterior pituitary hormone ACTH leading to Cushing syndrome

Tumors that present with **PSaMMOMA** bodies: - **P**: _____ - **S**: Somatostatinoma - **M**: Meningioma - **M**: Malignant mesothelioma - **O**: Ovarian serous papillary cystadenocarcinoma - **M**: Milk (prolactinoma) - **A**: Adenocarcinoma (Endometrial serous)

_____ syndrome is a combination of familial adenomatous polyposis with osteomas and fibromatosis

Some _____ secrete PTH-related peptide (PTH-rp), which is structurally homologous with the PTH secreted by the parathyroid glands

Acoustic neuromas are _____ whereas glomus tumors are non-capsulated (capsulated/non-capsulated)

Invasive lobular carcinoma grows in a _____ pattern due to lack of E-cadherin encoded by gene CDH-1

One subtype of invasive ductal carcinoma (breast) is _____ carcinoma, which is characterized by an erythematous and swollen breast that does not resolve with antibiotics

_____ is a tumor suppressor gene whose product inhibits hypoxia-inducible factor 1α (HIF-1α)

Patients with a germline Rb mutation will typically develop a _____ Retinoblastoma, with an increased risk of osteosarcoma and pinealoblastoma ("trilateral" retinoblastoma)