Hematopathology — Flashcards

Flashcard 401: Against which RBC antigen are the IgM antibodies of cold agglutination reaction directed?_____

Answer: I/i antigen

Flashcard 402: The estimation of prothrombin time (PT) and activated Partial Thromboplastin Time (aPTT) requires platelet-_____ plasma

Answer: poor

Flashcard 403: Hemoglobin level associated with poor prognosis in Hodgkin Lymphoma (International Prognostic Score criteria)

Answer: < 10.5 g/dL

Extra: The International Prognostic Score (IPS) for Advanced Hodgkin Lymphoma (Hasenclever index) includes 7 factors: 1. Albumin < 4 g/dL 2. **Hemoglobin < 10.5 g/dL** 3. Male sex 4. Age ≥ 45 years 5. Stage IV disease 6. Leukocytosis (WBC ≥ 15,000/mm³) 7. Lymphocytopenia (< 600/mm³ or < 8% of differential)

Flashcard 404: On bone marrow biopsy, hairy cell leukemia will show a _____ appearance of leukemic cells

Answer: fried egg

Flashcard 405: Mesenteric group of lymph nodes and Waldeyer ring are frequently involved in a _____Hodgkin's lymphoma

Answer: Non-

Flashcard 406: What variant of Hodgkin's lymphoma is associated with maximum necrosis of the lymph nodes?_____

Answer: Lymphocyte depleted

Flashcard 407: Sago spleen is due to deposition of amyloid in follicles of _____ pulp.

Answer: white

Flashcard 408: The ratio between fat cells to hematopoietic elements in a normal adult is about _____

Answer: 1:1

Flashcard 409: College-girl or Garden party appearance in peripheral blood smear is described for _____ leukemia

Answer: chronic myeloid

Flashcard 410: _____ is the most sensitive marker of Reed Sternberg cell

Answer: CD30