Thrombotic Disorders — Flashcards

Flashcard 1: Disorders of primary hemostasis are divided into _____ and quantitative disorders

Answer: qualitative

Flashcard 2: Disseminated intravascular coagulation (DIC) as a paraneoplastic syndrome is most commonly associated with _____ and prostatic adenocarcinoma.

Answer: acute promyelocytic leukemia (APL)

Flashcard 3: Grey platelet syndrome is a disorder involving platelet _____ granules

Answer: alpha

Extra: Grey platelet syndrome (GPS) is characterized by a deficiency of alpha-granules, resulting in large, pale/grey platelets on peripheral smear and a bleeding tendency.

Flashcard 4: _____ is a qualitative platelet disorder due to a genetic GPIIb/IIIa deficiency

Answer: Glanzmann thrombasthenia

Flashcard 5: B-ALL with t(_____;22) has a poor prognosis and is more commonly seen in adults (age group)

Answer: 9

Flashcard 6: The _____ time is prolonged in patients with deficient or defective fibrinogen

Answer: thrombin

Flashcard 7: Deficiency of factor _____ is also referred to as parahemophilia

Answer: V

Flashcard 8: Which blood component has protein C/S and antithrombin?_____

Answer: FFP

Flashcard 9: Factor XIII deficiency presents with _____ prothrombin time (PT) and a normal activated partial thromboplastin (aPTT)

Answer: normal

Flashcard 10: What is the inheritence pattern of Glanzmann thrombasthenia?_____

Answer: Autosomal Recessive