Hematopathology — Flashcards

Flashcard 231: The transfusion of packed RBCs (PRBC) should be completed within a maximum period of _____ hours after the removal from the blood fridge.

Answer: 4

Flashcard 232: Inherited form of thrombotic thrombocytopenic purpura is also referred to as _____ syndrome

Answer: Upshaw-Schulman

Flashcard 233: HAM S test (acidified serum lysis) is used for the diagnosis of _____

Answer: Paroxysmal nocturnal hemoglobinuria

Flashcard 234: Large granular lymphocytic leukemia will have mutations in the _____ gene

Answer: STAT3

Flashcard 235: _____ is an aggressive lymphoid neoplasm that classically occurs in the oral cavity in immunosuppressed patients

Answer: Plasmablastic lymphoma

Flashcard 236: Which subtype of MGUS can progress to Waldenström macroglobulinemia?

Answer: IgM MGUS

Flashcard 237: In Small Lymphocytic Lymphoma (SLL), the absolute lymphocyte count is < _____ per mm³.

Answer: 5,000 (If ≥ 5,000, it is classified as CLL)

Extra: Small Lymphocytic Lymphoma (SLL) and Chronic Lymphocytic Leukemia (CLL) are biologically the same disease. The distinction is based on where the bulk of the disease is located and the peripheral blood count: - **SLL:** Lymphadenopathy + Absolute Lymphocyte Count (ALC) < 5,000/mm³ - **CLL:** ALC ≥ 5,000/mm³ (regardless of lymph node involvement)

Flashcard 238: What is the most common bilateral testicular tumors?_____

Answer: Lymphoma

Flashcard 239: What is the inheritence pattern of Bernard-Soulier syndrome?_____

Answer: Autosomal Recessive

Flashcard 240: Anaplastic large cell lymphoma is a _____-cell lymphoma with large lymphoid cells

Answer: T