Hematopathology — Flashcards

Flashcard 231: HAM S test (acidified serum lysis) is used for the diagnosis of _____

Answer: Paroxysmal nocturnal hemoglobinuria

Flashcard 232: What is the most common tumor arising due to ionizing radiation (medical imaging)?_____

Answer: Myeloid leukemia

Flashcard 233: Deficiency of factor _____ is also referred to as Stuart-prower disease

Answer: X

Flashcard 234: Large granular lymphocytic leukemia will have mutations in the _____ gene

Answer: STAT3

Flashcard 235: Hemophagocytic lymphohistiocytosis is characterized by low or absent _____ cell activity

Answer: NK

Flashcard 236: Which subtype of MGUS can progress to Waldenström macroglobulinemia?

Answer: IgM MGUS

Flashcard 237: The test for prothrombin time is done within _____ hours.

Answer: 24

Extra: According to CLSI H21-A5 guidelines and standard textbooks (e.g., Harsh Mohan Pathology), samples for Prothrombin Time (PT) are stable for up to 24 hours at room temperature (25°C). In contrast, Activated Partial Thromboplastin Time (APTT) samples are more labile and should be tested within 4 hours.

Flashcard 238: _____ is a marker for Waldenström macroglobulinemia

Answer: MYD88

Flashcard 239: _____ is an aggressive lymphoid neoplasm that classically occurs in the oral cavity in immunosuppressed patients

Answer: Plasmablastic lymphoma

Flashcard 240: What is the most common bilateral testicular tumors?_____

Answer: Lymphoma