Hematopathology — Flashcards

Flashcard 241: _____ protein deficiency is responsible for the mushroom cell shape of the RBCs

Answer: Band 3

Flashcard 242: _____ is a marker for Waldenström macroglobulinemia

Answer: MYD88

Flashcard 243: Delayed umbilical stump bleeding is characteristic of factor _____ deficiency.

Answer: XIII

Flashcard 244: The test for prothrombin time is done within _____ hours.

Answer: 24

Extra: According to CLSI H21-A5 guidelines and standard textbooks (e.g., Harsh Mohan Pathology), samples for Prothrombin Time (PT) are stable for up to 24 hours at room temperature (25°C). In contrast, Activated Partial Thromboplastin Time (APTT) samples are more labile and should be tested within 4 hours.

Flashcard 245: Lymph node biopsy of CLL will show loose aggregates of small lymphocytes and larger activated lymphocytes, commonly referred to as _____ centres

Answer: proliferation

Flashcard 246: Which form (primary or secondary) myelodysplastic syndrome show high risk of transforming to AML?_____

Answer: Secondary/therapy related

Flashcard 247: What AML subtype is associated with organ infiltration?_____

Answer: AML M5

Flashcard 248: What is the anticoagulant used in black coloured ESR vaccutainer?_____

Answer: Citrate

Flashcard 249: Do patients with juvenile CML have philadelphia chromosome?_____

Answer: No

Flashcard 250: Activation of the transcription factor _____ is a common event in classical Hodgkin's lymphoma (HL).

Answer: NF-κB