Hematopathology — Flashcards

Flashcard 221: Cryoprecipitate is stored at a temperature of _____ °C

Answer: -18°C or colder (commonly -30°C)

Extra: Cryoprecipitate is prepared by thawing Fresh Frozen Plasma (FFP) at 4°C and collecting the precipitate. Storage: - Frozen: -18°C or colder for up to 1 year. - Thawed: 20–24°C (room temperature); must be transfused within 6 hours (or 4 hours if pooled in an open system). Do NOT refrigerate after thawing as it causes reprecipitation of clotting factors. Contents: Fibrinogen, Factor VIII, Factor XIII, von Willebrand factor (vWF), and Fibronectin.

Flashcard 222: Most myelomas are associated with more than _____ gm/dL of serum Ig

Answer: 3

Flashcard 223: What is the confirmatory test for Factor XIII deficiency?_____

Answer: Urea lysis test

Flashcard 224: Biallelic mutation in CEBPA suggests a _____ prognosis for AML

Answer: good

Flashcard 225: Which AML subtype is also known as Schilling type?_____

Answer: AML M5 (monocytic or monoblastic)

Flashcard 226: Deficiency of factor _____ is also referred to as Stuart-prower disease

Answer: X

Flashcard 227: HAM S test (acidified serum lysis) is used for the diagnosis of _____

Answer: Paroxysmal nocturnal hemoglobinuria

Flashcard 228: If the Mentzer index is _____, the patient likely has iron deficiency anemia.

Answer: > 13

Flashcard 229: The transfusion of packed RBCs (PRBC) should be completed within a maximum period of _____ hours after the removal from the blood fridge.

Answer: 4

Flashcard 230: What is the most common tumor arising due to ionizing radiation (medical imaging)?_____

Answer: Myeloid leukemia