Hematopathology — Flashcards

Flashcard 211: _____ body is a drumstick shaped mass of chromatin hanging down from neutrophil nuclei

Answer: Davidson

Flashcard 212: Hodgkin lymphoma has a bimodal distribution: common in _____ and adults > 55 years

Answer: young adulthood

Flashcard 213: _____ will show decreased mean fluorescence of RBCs in eosin 5-maleimide (EMA) binding test

Answer: Hereditary spherocytosis

Flashcard 214: DCIP test is a test-tube turbidity test used for the screening of hemoglobin _____

Answer: E

Flashcard 215: Which white blood cells can be elevated in patients of polycythemia vera?_____

Answer: Basophils and eosinophils

Flashcard 216: In atypical chronic myeloid leukemia (aCML), monocytes typically constitute what percentage of the white blood cell count?

Answer: < 10%

Extra: Atypical chronic myeloid leukemia (BCR-ABL1 negative) is a myelodysplastic/myeloproliferative neoplasm (MDS/MPN) characterized by leukocytosis and prominent granulocytic dysplasia. One of the diagnostic criteria to distinguish aCML from CMML is that monocytes must constitute < 10% of the total white blood cell count.

Flashcard 217: Cryoprecipitate is stored at a temperature of _____ °C

Answer: -18°C or colder (commonly -30°C)

Extra: Cryoprecipitate is prepared by thawing Fresh Frozen Plasma (FFP) at 4°C and collecting the precipitate. Storage: - Frozen: -18°C or colder for up to 1 year. - Thawed: 20–24°C (room temperature); must be transfused within 6 hours (or 4 hours if pooled in an open system). Do NOT refrigerate after thawing as it causes reprecipitation of clotting factors. Contents: Fibrinogen, Factor VIII, Factor XIII, von Willebrand factor (vWF), and Fibronectin.

Flashcard 218: What is the confirmatory test for Factor XIII deficiency?_____

Answer: Urea lysis test

Flashcard 219: Most myelomas are associated with more than _____ gm/dL of serum Ig

Answer: 3

Flashcard 220: Most efficient method for performing leukoreduction is the use of specific _____ filters

Answer: 3rd generation (leukocyte-reduction)