Nucleic Acid Biochemistry — Flashcards

RNA polymerase _____ makes tRNA and 5S rRNA

The enzyme _____ is an important enzyme for de novo purine production, which converts PRPP to an intermediate used in the generation of IMP

The _____ operon is a repressible operon that is turned off whenever tryptophan is added to the growth medium.

DNA & RNA are made of _____ connected via a phosphodiester bond

Diphtheria toxin causes _____ of EF-2 (elongation factor-2), thus inhibiting protein synthesis

The _____ bond of DNA is the target of 3' hydroxyl attack (strand elongation)

Cells generate purines for cell growth through either _____ production or through the salvage pathway

_____ radiation results in the formation of double-stranded breaks in DNA and hydroxyl free radicals which damage DNA

All 4 types of DNA are _____ handed except Z-DNA

_____ inhibits ribonucleotide reductase, which normally catalyzes conversion of UDP to dUDP (pyrimidine synthesis)