Nucleic Acid Biochemistry — Flashcards

Xanthine is converted to _____ by xanthine oxidase

One co-transcriptional modification is the addition of a _____ at the 5' end

Carbamoyl phosphate is combined with _____ to form orotic acid (pyrimidine synthesis)

The enzymes that repair mismatched base mutations (eg. spontaneous/toxic deaminations) are _____ and DNA ligase

Which base excision repair enzymes are responsible for filling and sealing the gap from the excised bases?_____ (filling) and DNA ligase III (sealing)

Hint: specific

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

Hypoxanthine is converted to _____ via xanthine oxidase

Conversion of dUMP to dTMP via Thymidylate synthase converts the cofactor _____ to DHF

Ribose-5-phosphate is converted to _____ via the enzyme PRPP synthetase

Hypoxanthine may be converted to _____ via the enzyme xanthine oxidase and guanine is converted to xanthine by guanine deaminase