Metabolic Integration — Flashcards

During fasting and starvation, the priority is to supply sufficient glucose to the _____ and RBCs while preserving protein

_____ activates factor VII, which initiates the extrinsic pathway of the coagulation cascade

The number of insulin receptors is _____ in starvation and decreased in obesity

Which metabolic enzymes require an obligate activator? 1. _____2. Carbamoyl phosphate synthetase I (N-acetylglutamate)

Which metabolic pathways require an obligate activator? 1. _____2. Urea cycle

Pyruvate kinase is regulated via negative feedback by _____ and alanine

_____ is an intermediate of cholesterol synthesis that is important for synthesis of coenzyme Q (ETC)

Increased NADH/NAD+ (e.g. due to ethanol) causes decreased TCA activity, thus increasing utilization of acetyl-CoA for _____ and lipogenesis

11-deoxycorticosterone (DOC) may be converted to _____ via the enzyme 11-hydroxylase

In starvation, the enzyme 5'-deiodinase is _____ in tissues such as skeletal muscle, but not inhibited in the other tissues, such as the brain