Metabolic Regulation: Substrate Availability — Flashcards

Glucagon acts on the _____ (primarily) and adipose tissue

After three days of starvation, the main source of energy for the brain becomes _____ from adipose stores

Which metabolic enzymes require an obligate activator? 1. _____2. Carbamoyl phosphate synthetase I (N-acetylglutamate)

_____ reactions are chemical reactions that form intermediates of a metabolic pathway.

Glucagon causes _____ fatty acid synthesis and increased lipolysis, which shunts substrates towards gluconeogenesis

_____ deficiency causes a buildup of pyruvate that gets shunted to lactate (via LDH) and alanine (via ALT)

Effect of diabetes on hepatic glycolysis: _____ - Lack of PFK-2 activity due to low insulin - Impaired glucose trapping (reduced glucokinase) in the liver leads to hyperglycemia