Muscle Metabolism — Flashcards

Which metabolic pathways require an obligate activator? 1. _____2. Urea cycle

After three days of starvation, the main source of energy for the brain becomes _____ from adipose stores

Thyroid hormone increases the processes of _____, gluconeogenesis, proteolysis, and lipolysis, all of which may provide sources of ATP

Which metabolic enzymes require an obligate activator? 1. _____2. Carbamoyl phosphate synthetase I (N-acetylglutamate)

In starvation, the enzyme 5'-deiodinase is _____ in tissues such as skeletal muscle, but not inhibited in the other tissues, such as the brain

In a person starving for more than 18 hours, the source of energy is _____.

Effect of diabetes on hepatic glycolysis: _____ - Lack of PFK-2 activity due to low insulin - Impaired glucose trapping (reduced glucokinase) in the liver leads to hyperglycemia

_____ deficiency causes a buildup of pyruvate that gets shunted to lactate (via LDH) and alanine (via ALT)

Glucagon acts on the _____ (primarily) and adipose tissue

Glucagon causes _____ fatty acid synthesis and increased lipolysis, which shunts substrates towards gluconeogenesis