NEET-PG 2015 Practice Questions

Q: In cobalamin deficiency which is not seen

Microcytic anemia. Microcytic anemia - Cobalamin deficiency typically leads to macrocytic anemia due to impaired DNA synthesis, not microcytic anemia [1]. - Microcytic anemia is usually associated with iron deficiency, thalassemia, or anemia of chronic disease [1]. Long tract signs - Long tract signs are common in cobalamin deficiency due to posterior column and corticospinal tract involvement leading to symptoms like spasticity. - They indicate involvement of pathways that are affected by vitamin B12 deficiency. Loss of proprioception - Loss of proprioception can occur in cobalamin deficiency due to damage to the dorsal columns of the spinal cord. - It is a common clinical finding indicating the involvement of sensory pathways. Rhomberg sign - A positive Rhomberg sign indicates impaired proprioception, which can happen in cobalamin deficiency. - It reflects difficulty maintaining balance, emphasizing sensory dysfunction associated with the deficiency.

Q: All of the following are clinical features suggestive of tracheoesophageal fistula except -

Fever. ***Fever*** - **Fever is NOT a primary clinical feature** of tracheoesophageal fistula (TEF) itself. - While fever might occur as a **complication** if aspiration pneumonia develops, it is not a direct presenting sign of TEF. - The classic presentation of TEF occurs in **newborns within hours of birth** and involves the "3 Cs" - not fever. *Choking and Coughing* - Part of the classic **"3 Cs" triad** (Choking, Coughing, Cyanosis) of TEF presentation. - Occurs during the **first feeding attempt** when milk enters the trachea through the abnormal fistulous connection. - This is a **cardinal diagnostic feature** that should immediately raise suspicion for TEF. *Regurgitation* - **Immediate regurgitation** of feeds is characteristic, especially in TEF with esophageal atresia (most common type - Type C). - The **blind-ending proximal esophageal pouch** prevents normal passage of saliva and feeds, causing regurgitation. - Often accompanied by **excessive drooling and frothy secretions** from the mouth and nose. *Cyanosis* - The third component of the **"3 Cs" triad** and a key clinical feature. - Results from **aspiration of feeds or saliva** into the trachea and lungs, causing acute respiratory distress. - May also occur from **laryngospasm** as a protective reflex when fluid enters the airway.

Q: Rigler's sign is suggestive of?

Pneumoperitoneum. ***Correct: Pneumoperitoneum*** - **Rigler's sign** (double wall sign) is the visualization of both the **inner (mucosal) and outer (serosal) surfaces** of the bowel wall on an abdominal X-ray. - This occurs when **free intraperitoneal air** outlines both sides of the bowel wall, making it a **pathognomonic sign of pneumoperitoneum**. - Commonly seen in **bowel perforation** from causes like peptic ulcer, trauma, or iatrogenic injury. *Incorrect: Pneumothorax* - Refers to air in the **pleural space** (thoracic cavity), not the peritoneal cavity. - Diagnosed on chest X-ray by the **visceral pleural line** with absent lung markings peripherally. - Completely different anatomical compartment from where Rigler's sign is observed. *Incorrect: Peritonitis* - Represents **inflammation of the peritoneum**, which is a clinical and pathological diagnosis. - While pneumoperitoneum from perforation can **lead to peritonitis**, Rigler's sign specifically indicates the **presence of free air**, not inflammation itself. - Peritonitis has no specific pathognomonic radiological sign like Rigler's. *Incorrect: Hemothorax* - Refers to **blood in the pleural cavity** (thoracic, not abdominal). - Appears as a **pleural effusion** with meniscus sign on chest X-ray. - Unrelated to abdominal radiological findings or free air.

Q: Which of the following stoma is formed in Hartmann's procedure?

End Colostomy. ***End Colostomy*** - Hartmann's procedure involves resection of a diseased segment of the **colon**, typically the sigmoid colon, with the creation of a **proximal colostomy** and closure of the distal rectal stump. - The proximal end of the colon is brought out through the abdominal wall to form a **stoma**, which is a type of end colostomy. *End Ileostomy* - An end ileostomy involves bringing the **ileum** (small intestine) to the abdominal wall, which is not part of the standard Hartmann's procedure. - This is typically performed after a **total colectomy** or in cases of severe Crohn's disease affecting the colon. *Loop Ileostomy* - A loop ileostomy involves bringing a **loop of the ileum** to the surface of the abdomen, creating two openings that are then joined together. - This is often a **temporary diversion** and does not involve resection of the colon in the same manner as Hartmann's procedure. *Caecostomy* - A caecostomy is a stoma created from the **cecum**, the beginning of the large intestine. - This is typically performed for various reasons such as **bowel decompression** or management of fecal incontinence, and is not a component of Hartmann's procedure.

Q: A 70 year old male complaining of per rectal bleeding was diagnosed with rectal/anorectal cancer. The distal margin of the tumor was 5 cm from the anal verge. The treatment of choice would be -

Low anterior resection. ***Low anterior resection*** - A tumor located 5 cm from the anal verge is considered a **low rectal tumor**, which is typically amenable to a **low anterior resection** with sphincter preservation. - This procedure aims for complete tumor removal while preserving anal function, which is often achievable when the distal margin allows for a safe distal resection margin (usually 1-2 cm). *Palliative Radiotherapy* - This is typically reserved for patients with advanced, **unresectable disease** or those who are not candidates for surgery due to comorbidities, aiming to alleviate symptoms rather than cure. - The scenario describes a potentially resectable tumor, making curative surgery the preferred initial approach. *Abdominoperineal resection* - This procedure involves the removal of the rectum, anus, and creation of a permanent colostomy, typically reserved for very **low rectal tumors** that are extremely close to or involve the anal sphincter, and cannot safely achieve a negative distal margin with sphincter preservation. - A tumor 5 cm from the anal verge usually allows for a sphincter-sparing procedure like low anterior resection. *Local Excision* - **Local excision (transanal excision)** is suitable for very superficial, small, well-differentiated tumors without lymph node involvement, typically T1N0M0 tumors. - The question does not provide details on tumor depth or nodal status, but a 5 cm tumor usually indicates a need for a more comprehensive resection to ensure oncological clearance.

Q: Which of the following statements about Hirschsprung disease is incorrect?

The non-peristaltic affected segment is dilated. ***The non-peristaltic affected segment is dilated*** - In Hirschsprung disease, the **aganglionic segment** is typically **constricted** and **narrow**, not dilated, due to continuous contraction without relaxation. - The healthy colon proximal to the affected segment becomes dilated due to the obstruction caused by the constricted, aganglionic segment. *Absence of Ganglion cells in the involved segment* - This statement is **correct**. Hirschsprung disease is fundamentally characterized by the **absence of intramural ganglion cells** (Meissner and Auerbach plexuses) in a segment of the distal colon. - This aganglionosis results in a failure of relaxation and normal peristalsis in the affected bowel segment. *Swenson, Duhamel, and Soave are surgical procedures for this condition* - This statement is **correct**. These are the classic and most common **pull-through surgical procedures** used to treat Hirschsprung disease. - They involve resecting the aganglionic segment and pulling the normal, ganglionated bowel down to the anus. *Mainly presents in infancy* - This statement is **correct**. Hirschsprung disease is primarily a **congenital condition** and is typically diagnosed in newborns and infants. - Common presenting symptoms include **failure to pass meconium** within the first 24-48 hours of life, abdominal distension, and bilious vomiting.

Q: Among pathological lead points, the commonest cause of intussusception is -

Meckel's diverticulum. ***Meckel's diverticulum*** - Among **pathological lead points** specifically, **Meckel's diverticulum** is the most common cause of intussusception. - It is a true congenital diverticulum that can act as a lead point when it becomes inverted, inflamed, or has associated ectopic tissue or tumors. - While overall intussusception in children is mostly idiopathic, when a **pathological lesion** is identified, Meckel's diverticulum is the leading cause. - Seen in approximately 2% of the population, it follows the "rule of 2s" and is the most frequent anatomical abnormality causing pathological intussusception in pediatric patients. *Hypertrophy of submucous Peyer's patches* - **Peyer's patch hypertrophy** is the most common cause of intussusception **overall** in children (90% of cases), typically following viral infections. - However, this represents **idiopathic intussusception**, not a true pathological lead point, as no discrete anatomical lesion is identified. - The question specifically asks for pathological lead points, which excludes this idiopathic mechanism. *Submucous lipoma* - A **submucous lipoma** can serve as a pathological lead point for intussusception, but is much rarer. - More commonly seen in adults rather than children. - While it is a true pathological lesion, it is less frequent than Meckel's diverticulum as a lead point. *Polyp* - **Polyps** (adenomatous, hamartomatous, or inflammatory) can act as pathological lead points. - More common in adults and in specific syndromes (e.g., Peutz-Jeghers syndrome). - Less frequent than Meckel's diverticulum among pathological causes in the pediatric population.

Q: What is the most important presenting feature of periampullary carcinoma?

Jaundice. ***Jaundice*** - **Painless obstructive jaundice** is the hallmark symptom, occurring early due to the tumor's proximity to the common bile duct. - The obstruction of bile flow leads to the accumulation of **bilirubin**, causing yellow discoloration of the skin and eyes. *Abdominal Pain* - While **abdominal pain** can occur, it is often a later symptom and is less specific than jaundice for early diagnosis. - Pain typically arises from tumor growth, invasion of surrounding structures, or pancreatic involvement. *Unintentional Weight Loss* - **Unintentional weight loss** is a common constitutional symptom of many advanced malignancies, including periampullary carcinoma. - However, it usually manifests at a later stage and is not the initial, specific presenting feature that prompts investigation. *Palpable Abdominal Mass* - A **palpable abdominal mass** is rare in early periampullary carcinoma, as these tumors are typically small and deeply seated. - Its presence usually indicates advanced disease with significant tumor burden or metastasis.

Question 1

In cobalamin deficiency which is not seen

Accepted Answer

Microcytic anemia

Answer

Loss of proprioception

Answer

Rhomberg sign

Answer

Long tract signs

Question 2

All of the following are clinical features suggestive of tracheoesophageal fistula except -

Accepted Answer

Fever

Answer

Choking and Coughing

Answer

Regurgitation

Answer

Cyanosis

Question 3

A patient undergoing a minor surgical procedure is given lignocaine injection. Assertion: Local anaesthetics act by blocking nerve conduction. Reason: Small fibers and non-myelinated fibers are blocked more easily than large myelinated fibers.

Accepted Answer

Both Assertion and Reason are true, and Reason is not the correct explanation for Assertion

Answer

Assertion is false, but Reason is true

Answer

Both Assertion and Reason are true, and Reason is the correct explanation for Assertion

Answer

Assertion is true, but Reason is false

Question 4

Rigler's sign is suggestive of?

Accepted Answer

Pneumoperitoneum

Answer

Pneumothorax

Answer

Peritonitis

Answer

Hemothorax

Question 5

Which of the following stoma is formed in Hartmann's procedure?

Accepted Answer

End Colostomy

Answer

End Ileostomy

Answer

Loop Ileostomy

Answer

Caecostomy

Question 6

A 55 year old woman presented with history of recurrent episodes of right upper abdominal pain for the last one year. She presented to emergency with history of jaundice and fever for 2 days. On examination, the patient appeared toxic and had a blood pressure of 100/60 mmHg. She was started on intravenous antibiotics. Ultrasound of the abdomen showed presence of stones in the common bile duct. What would be the best treatment option for her -

Accepted Answer

Endoscopic Retrograde Cholangiopancreatography (ERCP) and bile duct stone extraction

Answer

Open bile duct surgery for stone removal

Answer

Lithotripsy for bile duct stones

Answer

Laparoscopic cholecystectomy (gallbladder removal)

Question 7

A 70 year old male complaining of per rectal bleeding was diagnosed with rectal/anorectal cancer. The distal margin of the tumor was 5 cm from the anal verge. The treatment of choice would be -

Accepted Answer

Low anterior resection

Answer

Palliative Radiotherapy

Answer

Local Excision

Answer

Abdominoperineal resection

Question 8

Which of the following statements about Hirschsprung disease is incorrect?

Accepted Answer

The non-peristaltic affected segment is dilated

Answer

Absence of ganglion cells in the involved segment

Answer

Mainly presents in infancy

Answer

Swenson, Duhamel, and Soave are surgical procedures for this condition

Question 9

Among pathological lead points, the commonest cause of intussusception is -

Accepted Answer

Meckel's diverticulum

Answer

Submucous lipoma

Answer

Polyp

Answer

Hypertrophy of submucous peyer's patches

Question 10

What is the most important presenting feature of periampullary carcinoma?

Accepted Answer

Jaundice

Answer

Abdominal Pain

Answer

Unintentional Weight Loss

Answer

Palpable Abdominal Mass

NEET-PG 2015

Internal Medicine

Pediatrics

Pharmacology

Radiology

Surgery