NEET-PG 2013 Practice Questions

Q: In a 3 month fetus, characteristic feature seen is:

Nails are visible. ***Nails are visible*** - By the end of the **third month** (approximately 12 weeks), the fingers and toes are fully formed, and the beginnings of fingernails and toenails usually become visible. - This marks a significant developmental milestone in fetal maturation during the first trimester. *Meconium is present in the intestines* - **Meconium** begins to form during the **second trimester**, typically around weeks 12-16, with significant accumulation in the latter part of the second and throughout the third trimester. - While some gut movements occur earlier, the presence of well-formed meconium for defecation happens later in fetal development. *Anus formation begins* - The formation of the anus is part of the development of the **cloaca**, which begins much earlier, around the **4th to 7th gestational weeks**. - By 3 months, the anorectal canal is already well-differentiated, so its formation has already been completed. *Limb buds are present* - **Limb buds** appear very early in embryonic development, around the **end of the 4th week**. [1] - By 3 months, the limbs are already well-developed with distinct fingers and toes, so these structures would have passed the "bud" stage.

Q: Cobras belong to:

Elapidae. ***Elapidae*** - The family **Elapidae** includes cobras, mambas, kraits, and coral snakes, all of which are recognized by their **fixed front fangs** and potent neurotoxic venom. - Elapid venom typically affects the **nervous system**, causing paralysis and respiratory failure. *Colubridae* - This is the **largest snake family**, but most species are **non-venomous** or have mild venom and rear-fanged dentition. - Examples include rat snakes, garter snakes, and king snakes, which are generally not considered as dangerous as elapids. *Boidae* - Boidae are a family of **non-venomous, constricting snakes** that include boas, pythons, and anacondas. - They kill their prey by **suffocation** rather than venom. *Viperidae* - This family includes vipers and pit vipers, characterized by their **long, hinged fangs** that fold back when not in use. - Their venom is often **hemotoxic**, causing tissue damage and bleeding, and includes species like rattlesnakes and adders.

Q: Among the following countries, the first systematic fingerprint identification service was established in:

India. ***India*** - The **first systematic fingerprint identification service** was established in **Calcutta (now Kolkata), India in 1897** by Sir Edward Henry while he was Inspector General of Police in Bengal. - Henry developed the **Henry Classification System** in India, which became the standard fingerprint classification method worldwide. - This preceded the establishment of similar services in other countries, making it the first organized, systematic fingerprint bureau for criminal identification. *England* - England established its fingerprint bureau at **Scotland Yard in 1901**, four years after India. - Sir Edward Henry, who had developed the system in India, became Commissioner of the Metropolitan Police and established the Fingerprint Branch in London. - While England popularized fingerprint identification globally, it was not the first to establish a systematic service. *China* - **Ancient China** has historical evidence of using fingerprints on documents and clay seals for identification purposes dating back thousands of years. - However, this was not a systematic, scientific service for criminal identification in the modern sense with a classification system and organized bureau. *Singapore* - Singapore's forensic services, including fingerprint identification, developed later in the 20th century. - It followed the advancements pioneered by India and England and was not among the first countries to establish such services.

Q: 'Phossy jaw' is seen in chronic poisoning with:

Phosphorus. ***Phosphorus*** - **"Phossy jaw"** refers to the severe osteonecrosis of the jaw, historically seen in workers exposed to **white or yellow phosphorus**, particularly in the matchstick industry. - Exposure to **elemental phosphorus** leads to the destruction of bone tissue, infection, and eventually necrosis of the jawbone. *Arsenic* - Chronic arsenic poisoning primarily affects the **skin (hyperkeratosis, hyperpigmentation)**, and multiple organ systems. - It is not associated with **osteonecrosis of the jaw**. *Thallium* - Thallium poisoning is characterized by **alopecia**, **neuropathy**, and gastrointestinal symptoms. - It does not cause **"phossy jaw"**. *Datura* - Datura refers to a genus of plants containing **tropane alkaloids**, which cause anticholinergic toxidrome. - Symptoms include **dilated pupils**, dry mouth, hallucinations, and tachycardia, not jaw necrosis.

Q: What is the characteristic pupil condition seen in opium poisoning?

Miosis. ***Miosis*** - **Opioids** stimulate mu-opioid receptors in the brainstem, leading to increased parasympathetic outflow to the **oculomotor nerve**. - This stimulation causes constriction of the **pupillary sphincter muscle**, resulting in pinpoint pupils. *Mydriasis* - **Mydriasis** (dilated pupils) is typically caused by anticholinergic agents, sympathetic stimulation, or certain stimulants, which are not characteristic of opium poisoning. - While dilated pupils can occur in severe terminal hypoxia due to brainstem damage, this is not the initial or characteristic presentation of opioid toxicity. *No change* - **Opioid poisoning** reliably causes a distinct pupillary response, making "no change" an incorrect option for characteristic presentation. - The pupillary response is a crucial diagnostic sign for opioid intoxication. *Irregular* - **Irregular pupils** (dyscoria) are usually associated with direct ocular trauma, neurological conditions affecting specific parts of the iris, or certain inflammatory conditions of the eye. - This is not a typical finding in **opioid toxicity**, which causes symmetrically constricted pupils.

Q: Borax causes which of the following effects?

Causes gastrointestinal irritation (side effect). ***Causes gastrointestinal irritation (side effect)*** - Borax, specifically its component **boric acid**, is rapidly absorbed through the **gastrointestinal tract** and can cause symptoms like nausea, vomiting, and diarrhea even in small amounts. - This **gastrointestinal irritation** is a common sign of acute borax toxicity. *Induces uterine contractions (labor-inducing)* - While certain substances can induce uterine contractions, **borax is not known** or traditionally used for this purpose. - It is **not an oxytocic agent** and does not act on uterine smooth muscle in a way that would induce labor. *Irritates genitourinary tract (side effect)* - Although borax can be toxic, its primary route of significant irritation and toxicity is not typically the **genitourinary tract** in the way implied for adverse effects. - While it can be absorbed through mucous membranes, the genitourinary tract is not its primary target for **direct irritant effects** in systemic exposure. *Traditionally used to stimulate menstrual flow* - There is **no reliable scientific or traditional medical evidence** to support the use of borax to stimulate menstrual flow. - Substances used for this purpose, known as **emmenagogues**, are typically herbal or pharmaceutical preparations, and borax is **not among them**.

Q: Oximes are contraindicated in which poisoning:

Carbamate. ***Carbamate*** - Traditionally, oximes were considered **contraindicated** in carbamate poisoning based on concerns they could worsen the **cholinergic crisis** by reactivating carbamylated acetylcholinesterase. - Carbamates spontaneously **decarbamylate** from acetylcholinesterase within minutes to hours, so their inhibition is typically **short-lived and reversible**. - **Clinical relevance**: While modern evidence suggests oximes are more likely **ineffective** rather than harmful in carbamate poisoning, they are generally **not recommended** as they provide no therapeutic benefit. For exam purposes, particularly in historical contexts (NEET 2012-2013), carbamate poisoning is the answer for oxime contraindication. *Diazinon* - Diazinon is an **organophosphate**, and oximes like pralidoxime are **strongly indicated** for reactivating **acetylcholinesterase** inhibited by organophosphates. - Oximes are a crucial part of recommended antidotal therapy alongside **atropine** for severe organophosphate poisoning. - Must be administered early (within 24-48 hours) before **aging** of the phosphorylated enzyme occurs. *Phorate* - Phorate is a highly toxic **organophosphate pesticide**, and oximes are **indicated** for treatment of phorate poisoning. - Oximes work by **dephosphorylating** (nucleophilic attack on) the acetylcholinesterase enzyme, which has been inhibited by the organophosphate, restoring its catalytic function. *Malathion* - Malathion is an **organophosphate insecticide**, and oxime reactivators are **effective** in malathion poisoning. - The mechanism involves **cleaving the phosphate bond** from the serine residue on the acetylcholinesterase enzyme, allowing it to metabolize acetylcholine again and reverse cholinergic toxicity.

Q: Angel dust is:

Phencyclidine. ***Correct: Phencyclidine*** - **Phencyclidine (PCP)** is commonly known by the street name **"angel dust"** - It is a **dissociative anesthetic** with hallucinogenic and neurotoxic effects - Acts primarily as an **NMDA receptor antagonist** *Incorrect: LSD* - **LSD (lysergic acid diethylamide)** is a classic hallucinogen with the street name "acid," not angel dust - It primarily affects **serotonin receptors (5-HT2A)** and causes profound alterations in perception and thought - Chemically and pharmacologically distinct from PCP *Incorrect: Cannabis* - **Cannabis** is a psychoactive drug derived from the *Cannabis* plant, commonly known as marijuana or weed - Its active compound **THC (tetrahydrocannabinol)** produces euphoric and relaxing effects through cannabinoid receptors - Not related to the street name "angel dust" *Incorrect: Morphine* - **Morphine** is a potent **opioid analgesic** used for pain relief - Acts as a **CNS depressant** through mu-opioid receptors - Unlike PCP's dissociative and stimulant effects, morphine produces sedation and analgesia

Q: Severe mental retardation is:

20-35. ***20-35*** - A **score between 20-35** indicates **severe mental retardation**, where individuals typically have very limited communication skills and require extensive support in daily living activities. - This range is associated with significant cognitive impairment that often necessitates full-time supervision. *<20* - An **IQ score below 20** signifies **profound mental retardation**, indicating extremely limited intellectual functioning and severe developmental delays. - Individuals in this category generally have very minimal capacity for self-care or communication. *35-50* - This IQ range reflects **moderate mental retardation**, where individuals can often develop some basic communication and self-care skills, but still require significant support. - They may live semi-independently with supervision, but struggle with academic and complex social tasks. *50-70* - An **IQ score between 50-70** is classified as **mild mental retardation**, which is the most common form. - Individuals often achieve academic skills up to a 6th-grade level and can live independently with appropriate support.

Q: Periorbital ecchymosis without direct orbital trauma (raccoon eyes) is most commonly associated with injury to:

Base of skull. ***Base of skull*** - **Periorbital ecchymosis** (raccoon eyes) is a classic sign of a **basilar skull fracture**, particularly one involving the **anterior cranial fossa**. - The fracture allows blood to leak from the cranial cavity and track along fascial planes into the periorbital soft tissues. - The key feature is that ecchymosis occurs **without direct trauma to the orbit or eye**, indicating the primary injury is to the **skull base**. - Often associated with CSF rhinorrhea and requires CT imaging for diagnosis. *Eye* - The question specifically states the ecchymosis occurs "**without direct orbital trauma**," meaning the eye/orbit is NOT the site of injury. - The eye region is where the sign **manifests** (blood tracks to this area), but it is not the site of the underlying injury. - Direct eye trauma would cause immediate localized periorbital swelling, not the delayed bilateral "raccoon eyes" pattern. *Pinna* - Pinna (ear) injury can be associated with head trauma, and Battle's sign (retroauricular ecchymosis) indicates temporal bone fracture. - However, pinna injury does not cause periorbital ecchymosis; these are separate findings. *Scalp* - Scalp injuries cause localized bleeding and swelling at the impact site. - While scalp trauma may accompany basilar skull fracture, the scalp itself is not the source of periorbital ecchymosis. - Blood from scalp wounds tracks superficially, not into deep fascial planes leading to the orbits.

Question 1

In a 3 month fetus, characteristic feature seen is:

Accepted Answer

Nails are visible

Answer

Meconium is present in the intestines.

Answer

Anus formation begins.

Answer

Limb buds are present.

Question 2

Cobras belong to:

Accepted Answer

Elapidae

Answer

Colubridae

Answer

Boidae

Answer

Viperidae

Question 3

Among the following countries, the first systematic fingerprint identification service was established in:

Accepted Answer

India

Answer

England

Answer

China

Answer

Singapore

Question 4

'Phossy jaw' is seen in chronic poisoning with:

Accepted Answer

Phosphorus

Answer

Arsenic

Answer

Thallium

Answer

Datura

Question 5

What is the characteristic pupil condition seen in opium poisoning?

Accepted Answer

Miosis

Answer

Mydriasis

Answer

No change

Answer

Irregular

Question 6

Borax causes which of the following effects?

Accepted Answer

Causes gastrointestinal irritation (side effect)

Answer

Induces uterine contractions (labor-inducing)

Answer

Irritates genitourinary tract (side effect)

Answer

Traditionally used to stimulate menstrual flow

Question 7

Oximes are contraindicated in which poisoning:

Accepted Answer

Carbamate

Answer

Diazinon

Answer

Phorate

Answer

Malathion

Question 8

Angel dust is:

Accepted Answer

Phencyclidine

Answer

LSD

Answer

Cannabis

Answer

Morphine

Question 9

Severe mental retardation is:

Accepted Answer

20-35

Answer

<20

Answer

35-50

Answer

50-70

Question 10

Periorbital ecchymosis without direct orbital trauma (raccoon eyes) is most commonly associated with injury to:

Accepted Answer

Base of skull

Answer

Pinna

Answer

Scalp

Answer

Eye

NEET-PG 2013

Anatomy

Forensic Medicine

Pharmacology

Psychiatry

Surgery