Cardiology — Flashcards

Flashcard 3591: What neurologic complication is classically associated with **meperidine** overdose? _____

Answer: Seizures (due to the metabolite normeperidine)

Extra: While most opioids cause CNS depression, meperidine (and tramadol) are classically associated with seizures in overdose. Normeperidine has a long half-life and neurotoxic properties, especially in patients with renal impairment.

Flashcard 3592: What demographic (age, gender) is associated with scleroderma? _____

Answer: Middle-aged females (30-50 years)

Flashcard 3593: When does the rash of Rocky Mountain spotted fever (RMSF) typically appear?

Answer: 2–5 days after the onset of fever

Flashcard 3594: Granulomatosis with polyangiitis often presents with lower respiratory tract symptoms, such as _____, cough, and dyspnea

Answer: hemoptysis

Flashcard 3595: Which invasive infection can present similarly to mucormycosis (paranasal sinus necrosis)?_____

Answer: Invasive aspergillosis

Flashcard 3596: How do PCWP and preload change during cardiogenic and obstructive shock?

Answer: Increased ($\uparrow$)

Extra: In **cardiogenic shock** and most forms of **obstructive shock** (e.g., cardiac tamponade, tension pneumothorax), PCWP is increased. This helps differentiate them from hypovolemic and distributive shocks, where PCWP is decreased. **Note:** PCWP is actually decreased in obstructive shock caused by a massive pulmonary embolism (since the obstruction is proximal to the left atrium).

Flashcard 3597: Appropriate absolute polycythemia is characterized by _____ RBC mass

Answer: increased

Flashcard 3598: Hypertrophic cardiomyopathy may impair _____ valve closure, thus causing regurgitation

Answer: mitral

Flashcard 3599: Psoriatic arthritis characteristically involves the _____ joints of the hands and feet

Answer: DIP (distal interphalangeal) joints

Flashcard 3600: Lesions to the _____ lobe may present with re-emergence of primitive reflexes

Answer: frontal